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Berberine alleviates myocardial diastolic dysfunction by modulating Drp1-mediated mitochondrial fissionand Ca homeostasis in a murine model of HFpEF

Frontiers of Medicine doi: 10.1007/s11684-023-0983-0

Abstract: Berberine alleviates myocardial diastolic dysfunction by modulating Drp1-mediated mitochondrial fissionand Ca homeostasis in a murine model of HFpEF

Keywords： mitochondrial fission Ca     Berberine alleviates myocardial     murine model HFpEF    

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Modeling and simulation of droplet translocation and fission by electrowetting-on-dielectrics (EWOD)

Nathan HOWELL, Weihua LI

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 4,   Pages 376-388 doi: 10.1007/s11465-010-0104-z

Abstract: The two operations in focus here are droplet translocation (moving) and droplet fission (splitting),well as the creation of a tertiary droplet when the applied voltage causes a large enough force during fission

Keywords： electrowetting-on-dielectrics (EWOD)     electrowetting     microfluidics     droplet translocation     droplet fission    

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hydrophobic environment triggering reactive fluorescence probe to real-time monitor mitochondrial DNA

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 92-102 doi: 10.1007/s11705-021-2063-9

Abstract: Mitochondrial DNA has a special structure that is prone to damage resulting in many serious diseases,Therefore, the rapid and specific monitoring of mitochondrial DNA damage is urgently needed for biologicalIn this design, MBI-CN conjugates to mitochondrial DNA without causing additional damages.Give that the specific and rapid response of MBI-CN does not cause additional damages to mitochondrialDNA, it is a potentially effective detection tool for the real-time monitoring of mitochondrial DNA

Keywords： hydrolysis reaction     mitochondrial DNA damage     in situ hydrophobic environment trigger     fluorescence    

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Serum mitochondrial tsRNA serves as a novel biomarker for hepatocarcinoma diagnosis

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 216-226 doi: 10.1007/s11684-022-0920-7

Abstract: Hepatocellular carcinoma (HCC), which makes up the majority of liver cancer, is induced by the infection of hepatitis B/C virus. Biomarkers are needed to facilitate the early detection of HCC, which is often diagnosed too late for effective therapy. The tRNA-derived small RNAs (tsRNAs) play vital roles in tumorigenesis and are stable in circulation. However, the diagnostic values and biological functions of circulating tsRNAs, especially for HCC, are still unknown. In this study, we first utilized RNA sequencing followed by quantitative reverse-transcription PCR to analyze tsRNA signatures in HCC serum. We identified tRF-Gln-TTG-006, which was remarkably upregulated in HCC serum (training cohort: 24 HCC patients vs. 24 healthy controls). In the validation stage, we found that tRF-Gln-TTG-006 signature could distinguish HCC cases from healthy subjects with high sensitivity (80.4%) and specificity (79.4%) even in the early stage (Stage I: sensitivity, 79.0%; specificity, 74.8%; 155 healthy controls vs. 153 HCC patients from two cohorts). Moreover, in vitro studies indicated that circulating tRF-Gln-TTG-006 was released from tumor cells, and its biological function was predicted by bioinformatics assay and validated by colony formation and apoptosis assays. In summary, our study demonstrated that serum tsRNA signature may serve as a novel biomarker of HCC.

Keywords： tsRNA     biomarker     hepatocarcinoma    

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NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 263-274 doi: 10.1007/s11684-022-0935-0

Abstract: proliferation, malignant growth, migration, and invasion by downregulating the levels of calcium ions (Ca

Keywords： melanoma     neuropilin and tolloid-like 2     Ca2+/CaMKII signaling pathway    

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Conserved gene arrangement in the mitochondrial genomes of barklouse families Stenopsocidae and Psocidae

Xiaochen LIU, Hu LI, Yao CAI, Fan SONG, John-James WILSON, Wanzhi CAI

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 358-365 doi: 10.15302/J-FASE-2017158

Abstract: Substantial variation in gene organization and arrangement has been reported for sequenced mitochondrial

Keywords： gene rearrangement     mitochondrial genome     Psocoptera     Stenopsocidae     TDRL model    

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N-Positive ion activated rapid addition and mitochondrial targeting ratiometric fluorescent probes

Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 64-71 doi: 10.1007/s11705-021-2048-8

Abstract: In addition, cell imaging shows that this probe can be used for the mitochondrial targeted detection

Keywords： heterocyclic compound     hydrogen sulfide     ratiometric     mitochondrial targeted    

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Effect of K and Ca on catalytic activity of Mn-CeO

Boxiong SHEN, Lidan DENG, Jianhong CHEN

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 4,   Pages 512-517 doi: 10.1007/s11783-013-0519-y

Abstract: The poisoning of K and Ca on the catalyst of Mn-CeO /Ti-PILC is an important problem because K and CaTo investigate the effect of K and Ca on the physicochemical characters of the catalysts, the techniques(Ca)Mn-CeO /Ti-PILC and (K)Mn-CeO /Ti-PILC are denoted for the dopes of the catalyst of Mn-CeO /Ti-PILCwith Ca and K, respectively.decreased greatly, and K exhibited more poisoning effect than Ca.

Keywords： >x/Ti-pillared clay (PILC)     low-temperature selective catalytic reduction (SCR)     K and Ca    

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Protective roles of heat stress on the neurons in hippocampal CA1 region of mice

WANG Chunxu, WANG Hanxing

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 418-422 doi: 10.1007/s11684-007-0082-7

Abstract: The effects of heat stress on the neurons in hippocampal CA1 region of brain ischemia/reperfusion werememorizing, Nissl staining was used to count the average number of survived neurons in hippocampal CA1Nissl staining results showed a significant reduction in the number of pyramidal neurons in hippocampal CA1Compared with normal group, the expression of MAP-2 in hippocampal CA1 region obviously decreased in
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The role of fusion-fission hybrid reactor in development of China nuclear energy resources

Liu Cheng’an,Shi Xueming

Strategic Study of CAE 2011, Volume 13, Issue 3,   Pages 24-28

Abstract: the nuclear energy in the development of China energy resources and the important role of the fusion-fissiondevice as driving reactor core which could be realized in near future and water-cooled natural uranium fission

Keywords： hybrid reactor     fusion reactor core     fission blanked     fissile nucleus     fissionable nucleus    

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Laboratory study on high-temperature adsorption of HCl by dry-injection of Ca(OH)

Junjun TAN,Guohua YANG,Jingqiao MAO,Huichao DAI

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 6,   Pages 863-870 doi: 10.1007/s11783-013-0618-9

Abstract: experiments were conducted in a dual-layer granular bed filter, at gas temperatures of 500°C–700°C and (Ca)/ (Cl)molar ratios of 1.0–5.0 using the silver nitrate titration method by dry adsorbent powders Ca(of HCl and utilization efficiency of Calcium were studied, by varying relevant factors including (Caexperimental results revealed that 600°C may be the optimum temperature for HCl adsorption when optimum (Capressure was more effective, and the HCl adsorption efficiency could rapidly reach over 90% with (Ca

Keywords： acid gas HCl     Ca(OH)2     dry adsorption     high temperature     dual-layer granular bed filter    

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Research on Product Optimization Design Method to Respond Rapidly to Customer Requirements

Li Rupeng,Wei Wei,Zhou Feng,Zou Cheng

Strategic Study of CAE 2018, Volume 20, Issue 2,   Pages 33-41 doi: 10.15302/J-SSCAE-2018.02.006

Abstract: product optimization design via fuzzy clustering and conjoint analysis-quality function deployment (CA-QFDThe second is the new CA-QFD transformation method integrating conjoint analysis and traditional QFD,

Keywords： rapid response to customer requirements     fuzzy clustering     requirements transformation     CA-QFD method    

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NRTIs’ effect on the sequence of mitochondrial DNA HV 2 in HIV infected patients

Ya-Song WU MD, PhD, Xin-Yue CHEN MD, Ying SHI PhD, Hao WU MD, De-Xi CHEN MD, PhD, Yu SUN MD, Fu-Jie ZHANG MD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 177-184 doi: 10.1007/s11684-010-0038-1

Abstract: Direct DNA-sequencing analysis techniques were used to detect mitochondrial sequence variants between

Keywords： nucleoside reverse transcriptase inhibitors     human immunodeficiency virus     mitochondrial DNA     D loop     mutation    

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The engineering and technology progress of CAR-CA

Zhao Qinping

Strategic Study of CAE 2009, Volume 11, Issue 10,   Pages 25-31

Abstract: To meet the requirement of the design and manufacture of commercial aircraft in China, CAR-CA(collaborativeThis paper introduced the engineering and technology progress of CAR-CA, including the system architecture

Keywords： augmented reality     collaboration     cockpit     design     maintenance    

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Augmented hydrogen production by gasification of ball milled polyethylene with Ca(OH)

Giovanni Cagnetta, Kunlun Zhang, Qiwu Zhang, Jun Huang, Gang Yu

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 1, doi: 10.1007/s11783-019-1096-5

Abstract:

Ca(OH)2 reacts at solid state with

Ca(OH)2 significantly reduces methanation

Keywords： Hydrogen production     Gasification     Plastic waste     High energy ball milling    

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Title Author Date Type Operation

Berberine alleviates myocardial diastolic dysfunction by modulating Drp1-mediated mitochondrial fissionand Ca homeostasis in a murine model of HFpEF

Journal Article

Modeling and simulation of droplet translocation and fission by electrowetting-on-dielectrics (EWOD)

Nathan HOWELL, Weihua LI

Journal Article

hydrophobic environment triggering reactive fluorescence probe to real-time monitor mitochondrial DNA

Journal Article

Serum mitochondrial tsRNA serves as a novel biomarker for hepatocarcinoma diagnosis

Journal Article

NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Journal Article

Conserved gene arrangement in the mitochondrial genomes of barklouse families Stenopsocidae and Psocidae

Xiaochen LIU, Hu LI, Yao CAI, Fan SONG, John-James WILSON, Wanzhi CAI

Journal Article

N-Positive ion activated rapid addition and mitochondrial targeting ratiometric fluorescent probes

Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin

Journal Article

Effect of K and Ca on catalytic activity of Mn-CeO

Boxiong SHEN, Lidan DENG, Jianhong CHEN

Journal Article

Protective roles of heat stress on the neurons in hippocampal CA1 region of mice

WANG Chunxu, WANG Hanxing

Journal Article

The role of fusion-fission hybrid reactor in development of China nuclear energy resources

Liu Cheng’an,Shi Xueming

Journal Article

Laboratory study on high-temperature adsorption of HCl by dry-injection of Ca(OH)

Junjun TAN,Guohua YANG,Jingqiao MAO,Huichao DAI

Journal Article

Research on Product Optimization Design Method to Respond Rapidly to Customer Requirements

Li Rupeng,Wei Wei,Zhou Feng,Zou Cheng

Journal Article

NRTIs’ effect on the sequence of mitochondrial DNA HV 2 in HIV infected patients

Ya-Song WU MD, PhD, Xin-Yue CHEN MD, Ying SHI PhD, Hao WU MD, De-Xi CHEN MD, PhD, Yu SUN MD, Fu-Jie ZHANG MD,

Journal Article

The engineering and technology progress of CAR-CA

Zhao Qinping

Journal Article

Augmented hydrogen production by gasification of ball milled polyethylene with Ca(OH)

Giovanni Cagnetta, Kunlun Zhang, Qiwu Zhang, Jun Huang, Gang Yu

Journal Article